Brief Report on Gonadoblastoma

A team of Maltese researchers led by Prof Charles Savona-Ventura from the Department of Obstetrics and Gynaecology at the Faculty of Medicine and Surgery at the University of Malta have published a brief report on gonadoblastoma.

Gonadoblastoma is a rare tumour which typically occurs in dysgenetic gonads, but may occasionally also involve a normal ovary or
testis. Approximately 40% of such tumors are bilateral. Among affected individuals, up to 80% are phenotypic females and the rest are phenotypic males.  Gonadoblastomas are considered to be clinically benign neoplasms, but up to 50% are accompanied by foci of malignant germ cell tumor, mostly seminoma, and occasionally yolk sac tumor, embryonal carcinoma, choriocarcinoma or teratoma. This paper presents a brief literature review
based on a case of an XY female reared as male, with development of a gonadoblastoma in the left ovary.

This article has been published in the journal 'Annals of Research in Oncology'  and the editor-in-chief is Prof Antonio Giordano, who is the leader for Working Group 4 in the GYNOCARE COST Action.

Click here to read the full article.