Open Access Publications
Di Fiore R, Suleiman S, Ellul B, O'Toole SA, Savona-Ventura C, Felix A, Napolioni V, Conlon NT, Kahramanoglu I, Azzopardi MJ, Dalmas M, Calleja N, Brincat MR, Muscat-Baron Y, Sabol M, Dimitrievska V, Yordanov A, Vasileva-Slaveva M, von Brockdorff K, Micallef RA, Kubelac P, Achimaș-Cadariu P, Vlad C, Tzortzatou O, Poka R, Giordano A, Felice A, Reed N, Herrington CS, Faraggi D, Calleja-Agius J. GYNOCARE Update: Modern Strategies to Improve Diagnosis and Treatment of Rare Gynecologic Tumors—Current Challenges and Future Directions. Cancers (Basel). 2021 Jan 27;13(3):493. doi: 10.3390/cancers13030493. PMID: 33514073; PMCID: PMC7865420. Click here to read the full text.
Sabol M, Calleja-Agius J, Di Fiore R, Suleiman S, Ozcan S, Ward MP, Ozretić P. (In)Distinctive Role of Long Non-Coding RNAs in Common and Rare Ovarian Cancers. Cancers (Basel). 2021 Oct 9;13(20):5040. doi: 10.3390/cancers13205040. PMID: 34680193; PMCID: PMC8534192. Click here to read the full text.
Di Fiore R, Suleiman S, Pentimalli F, O'Toole SA, O'Leary JJ, Ward MP, Conlon NT, Sabol M, Ozretić P, Erson-Bensan AE, Reed N, Giordano A, Herrington CS, Calleja-Agius J. Could MicroRNAs Be Useful Tools to Improve the Diagnosis and Treatment of Rare Gynecological Cancers? A Brief Overview. Int J Mol Sci. 2021 Apr 7;22(8):3822. doi: 10.3390/ijms22083822. PMID: 33917022; PMCID: PMC8067678. Click here to read the full text.
Yordanov A, Kostov S, Slavchev S, Strashilov S, Konsoulova A, Calleja-Agius J, Di Fiore R, Suleiman S, Kubelac P, Vlad C, Achimas-Cadariu P, Vasileva-Slaveva M. Adenosquamous Carcinoma of the Uterine Cervix - Impact of Histology on Clinical Management. Cancer Manag Res. 2021 Jun 23;13:4979-4986. doi: 10.2147/CMAR.S311326. PMID: 34188551; PMCID: PMC8236277. Click here to read the full text.
Di Fiore R, Suleiman S, Felix A, O'Toole SA, O'Leary JJ, Ward MP, Beirne J, Sabol M, Ozretić P, Yordanov A, Vasileva-Slaveva M, Kostov S, Nikolova M, Said-Huntingford I, Ayers D, Ellul B, Pentimalli F, Giordano A, Calleja-Agius J. An Overview of the Role of Long Non-Coding RNAs in Human Choriocarcinoma. Int J Mol Sci. 2021 Jun 17;22(12):6506. doi: 10.3390/ijms22126506. PMID: 34204445; PMCID: PMC8235025. Click here to read the full text.
Subbannayya Y, Di Fiore R, Urru SAM, Calleja-Agius J. The Role of Omics Approaches to Characterize Molecular Mechanisms of Rare Ovarian Cancers: Recent Advances and Future Perspectives. Biomedicines. 2021 Oct 15;9(10):1481. doi: 10.3390/biomedicines9101481. PMID: 34680597; PMCID: PMC8533212. Click here to read the full text.
Di Fiore R, Suleiman S, Drago-Ferrante R, Felix A, O’Toole SA, O’Leary JJ, Ward MP, Beirne J, Yordanov A, Vasileva-Slaveva M, Subbannayya Y, Pentimalli F, Giordano A, Calleja-Agius J. LncRNA MORT (ZNF667-AS1) in Cancer—Is There a Possible Role in Gynecological Malignancies? International Journal of Molecular Sciences. 2021; 22(15):7829. Click here to read the full text.
Pisani D, Calleja-Agius J, Di Fiore R, O'Leary JJ, Beirne JP, O'Toole SA, Felix A, Said-Huntingford I. Epithelioid Trophoblastic Tumour: A Case with Genetic Linkage to a Child Born over Seventeen Years Prior, Successfully Treated with Surgery and Pembrolizumab. Current Oncology 2021 Dec 13;28(6):5346-5355. Click here to read the full text.
Di Fiore, R., Agius, A., Camenzuli, C., Suleiman, S., Calleja-Agius, J. & Savona-Ventura, C. (2022). Gonadoblastoma : a brief report. Annals of Research in Oncology, 2(1), 70-75. Click here to read the full text.
Di Fiore, R., Suleiman, S., Drago-Ferrante, R., Subbannayya, Y, Pentimalli, F., Giordano, A., Calleja-Agius, J., Cancer Stem Cells and Their Possible Implications in Cervical Cancer: A Short Review. Int. J. Mol. Sci. 2022, 23(9), 5167. Click here to read the full text.
Drago-Ferrante R, Di Fiore R, Karouia F, Subbannayya Y, Das S, Aydogan Mathyk B, Arif S, Guevara-Cerdán AP, Seylani A, Galsinh AS, Kukulska W, Borg J, Suleiman S, Porterfield DM, Camera A, Christenson LK, Ronca AE, Steller JG, Beheshti A, Calleja-Agius J. Extraterrestrial Gynecology: Could Spaceflight Increase the Risk of Developing Cancer in Female Astronauts? An Updated Review. Int J Mol Sci. 2022 Jul 5;23(13):7465. Click here to read the full text.
Tripac I, Calleja-Agius J, Harasani K, Kubelac P, Stratan V, Tutuianu V, Sitnic V, Dobrovolskaia A. Status of the Sentinel Lymph Node in Patients with Endometrial Cancer Stage I-II. Chirurgia (Bucur). 2022 Dec;117(6):689-697. doi: 10.21614/chirurgia.2786. PMID: 36584061. Click here to read the full text.
Yordanov A, Kostov S, Kornovski Y, Slavchev S, Ivanova Y, Calleja-Agius J, Di Fiore R, Suleiman S, Piciu A, Hasan I, Vasileva-Slaveva M. Endometrial carcinoma in patients under 40 years of age: insights from the bulgarian cancer registry. Ginekologia Polska. 2022 Oct 10. doi: 10.5603/GP.a2022.0106. Click here to read the full text.
Harasani K., Conlon N.T., Darmanin S., Čelebić A., Kubelac M.P., Lala A., Calleja-Agius J. Rapid systematic review of clinical trials on pharmacological therapies for rare gynecological cancers. Annals of Research in Oncology Vol. 2 (No. 4) 2022 December, 246-258. doi: 10.48286/aro.2022.57. Click here to read the full text.
Yordanov, A.; Vasileva-Slaveva, M.; Galai, N.; Faraggi, D.; Kubelac, M.P.; Tripac-Iacovleva, I.; Calleja, N.; Di Fiore, R.; Calleja-Agius, J. Cancer of the Cervix in Bulgaria: Epidemiology of a Crisis. Healthcare 2023, 11, 318. https://doi.org/10.3390/healthcare11030318. Click here to read the full text.
Agius A, Camenzuli C, Pisani D, Di Fiore R, Vella A, De Gaetano J, Vaitkiene D, Martins N, Calleja-Agius J (2023). A case report of HPV negative small cell neuroendocrine carcinoma and squamous cell carcinoma of the cervix: A rare but fatal mix. In Annals of Research in Oncology Vol. 3(1), 24-29, 2023;https://doi.org/10.48286/aro.2023.60. Click here to read full text.
Calleja-Agius J. (2023) Bridging the Gap between research and cure in rare gynaecological cancers: Where do we stand? Report from the GYNOCARE Conference in Naples (17-18th February 2023). In Annals of Research in Oncology Vol. 3(1), 35-56, 2023;https://doi.org/10.48286/aro.2023.62. Click here to read full text.
Irina T, Valentina S, Valeriu T, et al. #239 Analysis of the molecular profile of endometrial cancer depending on microsatelite instability International Journal of Gynecologic Cancer 2023;33:A143-A144. Click here to read full text.
Tripac I, Stratan V, Tutuianu V, et al 2022-RA-166-ESGO Prognostic significance of molecular genetic factors in endometrial cancer: a modern approach to the problem. International Journal of Gynecologic Cancer 2022;32:A88. Click here to read full text.
Frenel J, Guerin-Charbonnel C, Xu-Vuillard A, et al; #201 Real world evidence (RWE) on the efficacy of chemotherapy after progression during or following PARPi exposure in ovarian cancer: a multicentre, international study. International Journal of Gynecologic Cancer 2023;33:A257. Click here to read full text.
Kubelac P, Catalin V, Pasca A, et al, 2022-RA-1405-ESGO Indocyanine green in near-infrared light for intra-operative imaging of residual ovarian cancer after neoadjuvant chemotherapy. Initial experience. Published in International Journal of Gynecologic Cancer 2022;32:A333; https://doi.org/10.1136/ijgc-2022-ESGO.707. Click here to read full text.
Cheeseman S, Levick B, Sopwith W, Fenton H, Nam EJ, Kim D, Lim S, Martin E, Frenel J-S, Bocquet F, Kubelac P, Achimas-Cadariu P, Vlad C, Chevrier M, Rouzier R, Carton M, Savva-Bordalo J, Magalhães M, Borges M, Wolf A, Becker S, Niklas N, Guergova-Kuras M and Hall G (2023) Ovarian Real-World International Consortium (ORWIC): A multicentre, real-world analysis of epithelial ovarian cancer treatment and outcomes. Front. Oncol. 13:1114435. doi: 10.3389/fonc.2023.1114435. Click here to read full text.
Kubelac P, Avram A, Turcas A, et al #746 Molecular analysis of BRCA and hrd status from small biopsies in high grade serous carcinoma. a real-world comparative analysis
Calleja-Agius J. and Vasileva-Slaveva M. (2023) 'They are rare, but they are there’. Report from the GYNOCARE Training School in Sofia, Bulgaria (29th June-1st July 2023). In Annals of Research in Oncology Vol.3 (3) p.p. 132-134; doi: 10.48286/aro.2023.73. Click here to read full text.
Calleja-Agius J. and Vasileva-Slaveva M. (2023) 'Our battle for better healthcare is eternal'. Report from the GYNOCARE Conference in Sofia, Bulgaria (2nd-3rd July 2023). In Annals of Research in Oncology Vol.3 (3) p.p. 135-139; doi: 10.48286/aro.2023.74. Click here to read full text.
Vieira-Coimbra M, Nogueira-Martins N, Zadykowicz R, Gaspar HR, Calleja-Agius J, Pakiz M, Mukhopadhyay S, Mahmood T. EBCOG position statement on Inequalities in screening for cervical and breast cancer. Eur J Obstet Gynecol Reprod Biol. 2023 Oct;289:217-218. doi: 10.1016/j.ejogrb.2023.08.386. Epub 2023 Aug 30. PMID: 37689510. Click here to read full text.
Vieira-Coimbra M, Nogueira-Martins N, Zadykowicz R, Rodrigues Gaspar H, Calleja-Agius J, Pakiz M, Mukhopadhyay S, Mahmood T. Provision of screening services for cervical and breast cancer - A scientific study commissioned by the European Board & College of Obstetrics and Gynaecology (EBCOG). Eur J Obstet Gynecol Reprod Biol. 2023 Oct;289:208-216. doi: 10.1016/j.ejogrb.2023.08.385. Epub 2023 Aug 30. PMID: 37679212. Click here to read full text.
Tripac I, Agius JC, Harasani K, Kubelac P, Stratan V, Tutuianu V, Sitnic V, Dobrovolskaia A. Status of the Sentinel Lymph Node in Patients with Endometrial Cancer Stage I-II. Chirurgia (Bucur). 2022 Dec;117(6):689-697. doi: 10.21614/chirurgia.2786. PMID: 36584061. Click here to read full text.
Postema RR, Hardon S, Cefai D, Dankelman J, Jansen FW, Camenzuli C, Calleja-Agius J, Horeman-Franse T. Pre-clinical evaluation of the new veress needle+ mechanism on thiel-embalmed bodies: a controlled crossover study - Experimental research. Ann Med Surg (Lond). 2023 Apr 15;85(5):1371-1378. doi: 10.1097/MS9.0000000000000640. PMID: 37229054; PMCID: PMC10205261. Click here to read full text.
Postema, R.R., Cefai, D., van Straten, B. et al. A novel Veress needle mechanism that reduces overshooting after puncturing the abdominal wall. Surg Endosc 35, 5857–5866 (2021). https://doi.org/10.1007/s00464-021-08603-x. Click here to read full text.
Tripac I, Stratan V, Tutuianu V, et al. 2022-RA-807-ESGO MLH1 promoter methylation analysis in patients with endometrial cancer stage I-II
Di Fiore R, Suleiman S, Drago-Ferrante R, Subbannayya Y, Suleiman S, Vasileva-Slaveva M, Yordanov A, Pentimalli F, Giordano A, Calleja-Agius J. The Role of FBXW7 in Gynecologic Malignancies. Cells. 2023; 12(10):1415. https://doi.org/10.3390/cells12101415. Click here to read full text.
Calleja Agius J, Di Fiore R, Suleiman S, Savona-Ventura C: 2281. Gynocare COST Action CA18117 “European network for gynaecological rare cancer research: from concept to cure” in European Journal of Obstetrics & Gynecology and Reproductive Biology Volume 270, March 2022, Page e39. Click here to access full text.
Tripac I, Stratan V, Tutuianu V, Sitnic V, Calleja Agius J, Vasileva-Slaveva M, Kubelac MP, Catalin V; Harasani K, Bucinskii V, Japaridze N. Epigenetic silencing of MLH1 as a prognostic factor for endometrial cancer recurrence. International Journal of Gynecologic Cancer 2023;33:A131-A132. doi:10.1136/ijgc-2023-ESGO.272. Click here to read full text.
Coradduzza D, Bellu E, Congiargiu A, Pashchenko A, Amler E, Necas A, Carru C, Medici S, Maioli M. Role of Nano-miRNAs in Diagnostics and Therapeutics. International Journal of Molecular Sciences. 2022; 23(12):6836. https://doi.org/10.3390/ijms23126836. Click here to read full text.
Tzortzatou, Olga & Akyuz, Kaya & Goisauf, Melanie & Kozera, Łukasz & Mežinska, Signe & Mayrhofer, Michaela & Slokenberga, Santa & Reichel, Jane & Croxton, Talishiea & Ziaka, Alexandra & Makri, Marina. (2023). Ethical, legal, and social implications in research biobanking: A checklist for navigating complexity. Developing world bioethics. 10.1111/dewb.12411. Click here to read full text.
Casati, S., Ellul, B., Mezinska, S., Budin-Ljøsne, I., Tzortzatou, O., Bentzen, H. B., Jahns, R., Halouzka, R., & Mayrhofer, M. T. (2021). Mapping European RECs & ethics review processes for biobank-based research. Zenodo. https://doi.org/10.5281/zenodo.4573811. Click here to read full text.
Tzortzatou, Olga & Mezinska, Signe. (2021). Glossary Mapping European Research Ethics Committees & ethics review processes for biobank-based research. 10.5281/zenodo.4580480. Click here to read full text.
Akyuz, Kaya & Chassang, Gauthier & Goisauf, Melanie & Kozera, Łukasz & Mežinska, Signe & Tzortzatou, Olga & Mayrhofer, Michaela. (2021). Biobanking and risk assessment: a comprehensive typology of risks for an adaptive risk governance. Life Sciences, Society and Policy. 17. 10.1186/s40504-021-00117-7. Click here to read full text.
Casati S, Ellul B, Mayrhofer MT, Lavitrano M, Caboux E, Kozlakidis Z. Paediatric biobanking for health: The ethical, legal, and societal landscape. Front Public Health. 2022 Sep 27;10:917615. doi: 10.3389/fpubh.2022.917615. PMID: 36238242; PMCID: PMC9551217. Click here to read full text.
Books and Book Chapters
Di Fiore, R., Suleiman, S., Calleja-Agius, J. (2023). CD133 as Biomarker and Therapeutic Target in Gynecologic Malignancies. In: Interdisciplinary Cancer Research. Springer, Cham. https://doi.org/10.1007/16833_2023_139. Click here to read more.
Paruto G and Pegreffi F (2022) La Telemedicina nell'Assistenza Terapeutica e in particolare Oncologica. Bologna University Press. Click here to read full text.
Slokenberga, S; Tzortzatou, O; Reichel, J: GDPR and Biobanking: Individual Rights, Public Interest and Research Regulation across Europe (2021): DOI: 10.1007/978-3-030-49388-2. Click here to read whole book.
Tzortzatou, O. et al. (2021). Biobanking Across Europe Post-GDPR: A Deliberately Fragmented Landscape. In: Slokenberga, S., Tzortzatou, O., Reichel, J. (eds). GDPR and Biobanking. Law, Governance and Technology Series, vol 43. Springer, Cham. https://doi.org/10.1007/978-3-030-49388-2_22. Click here to read full text.